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Issue 9, 2002
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The potential for elemental analysis in biotechnology

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Abstract

The ICP-MS brings particular attributes to the method that distinguishes it from organic mass spectrometry: relative insensitivity to concomitant organic or metallic species, equivalent sensitivity to all similarly-tagged complexes, inherent ability to provide absolute quantitation and linearity of response. All these positive features fit the requirements of modern-day biotechnology. In this work, the potential of ICP-MS is discussed in the context of several urgent problems of biotechnology including: the determination of the state of phosphorylation of proteins, quality control of biologically active materials and control of efficiency of cell line transfections.

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Publication details

The article was received on 11 Feb 2002, accepted on 15 May 2002 and first published on 18 Jun 2002


Article type: Paper
DOI: 10.1039/B201494G
Citation: J. Anal. At. Spectrom., 2002,17, 1148-1152
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    The potential for elemental analysis in biotechnology

    V. I. Baranov, Z. A. Quinn, D. R. Bandura and S. D. Tanner, J. Anal. At. Spectrom., 2002, 17, 1148
    DOI: 10.1039/B201494G

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