Issue 20, 2002

DNA minor groove hydration probed with 4’-alkylated thymidines

Abstract

Employing modified oligonucleotides that are 4′-alkylated site-specifically we investigated the involvement of DNA minor groove hydration on DNA duplex stability and helix conformation.

Graphical abstract: DNA minor groove hydration probed with 4’-alkylated thymidines

Article information

Article type
Communication
Submitted
02 Aug 2002
Accepted
03 Sep 2002
First published
19 Sep 2002

Chem. Commun., 2002, 2314-2315

DNA minor groove hydration probed with 4’-alkylated thymidines

I. Detmer, D. Summerer and A. Marx, Chem. Commun., 2002, 2314 DOI: 10.1039/B207582M

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