Issue 8, 2002
From the journal:

Chemical Communications

New Pd-catalyzed selective reduction of carboxylic acids to aldehydes

Lukas J. Gooßen*a  and  Keya Ghosha  

* Corresponding authors

a Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, Mülheim an der Ruhr, Germany
E-mail: goossen@mpi-muelheim.mpg.de
Fax: +49-208-306-2985
Tel: +49-208-306-2392

Abstract

A catalyst generated in situ from palladium acetate and tricyclohexylphosphine efficiently catalyzes the reduction of carboxylic acids with sodium hypophosphite in the presence of pivalic anhydride to give aldehydes with high selectivity. The low cost and convenient handling of the reagents makes this process a valuable alternative to hydrogenations and metal hydride reductions.

Graphical abstract: New Pd-catalyzed selective reduction of carboxylic acids to aldehydes

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B201577N
Article type
Communication
Submitted
12 Feb 2002
Accepted
01 Mar 2002
First published
21 Mar 2002

Chem. Commun., 2002, 836-837

Permissions

Request permissions

New Pd-catalyzed selective reduction of carboxylic acids to aldehydes

L. J. Gooßen and K. Ghosh, Chem. Commun., 2002, 836 DOI: 10.1039/B201577N

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements