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Issue 22, 2002
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A paradigm for biological sulfur transfers via persulfide groups: a persulfide–disulfidethiol cycle in 4-thiouridine biosynthesis

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Abstract

In support of the key features of sulfur transfer in the proposed mechanisms of 4-thiouridine generation, the enzyme ThiI can turn over only once in the absence of reductants of disulfide bonds, and Cys-456 of ThiI receives the sulfur transferred from the persulfide group of the sulfurtransferase IscS.

Graphical abstract: A paradigm for biological sulfur transfers via persulfide groups: a persulfide–disulfide–thiol cycle in 4-thiouridine biosynthesis

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Publication details

The article was received on 03 Sep 2002, accepted on 01 Oct 2002 and first published on 18 Oct 2002


Article type: Communication
DOI: 10.1039/B208626C
Citation: Chem. Commun., 2002,0, 2708-2709
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    A paradigm for biological sulfur transfers via persulfide groups: a persulfide–disulfidethiol cycle in 4-thiouridine biosynthesis

    C. M. Wright, P. M. Palenchar and E. G. Mueller, Chem. Commun., 2002, 0, 2708
    DOI: 10.1039/B208626C

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