Jump to main content
Jump to site search

Issue 11, 2002
Previous Article Next Article

Determination of pentachlorophenol by negative ion chemical ionization with membrane introduction mass spectrometry

Author affiliations

Abstract

Pentachlorophenol (PCP) was used as a model compound to explore the potential of desorption chemical ionization (DCI) in the determination of polychlorinated pesticides using membrane introduction mass spectrometry (MIMS). A direct insertion membrane probe was modified so that a chemical ionization plasma could be established at the membrane surface. Using selected ion monitoring (SIM) in a tandem triple quadrupole mass spectrometer with isobutane chemical ionization (CI), the PCP detection limit under positive chemical ionization is 20 ppb whereas negative CI gives detection limits in the low ppb range. This performance is achieved without any pre-treatment or derivatization of the sample. Negative ion CI gives a signal that is linear over a concentration range of 2–1000 ppb. Comparison of data obtained with low ppb samples of 2,4,6-trichlorophenol, 2,3,4,6-tetrachlorophenol and pentachlorophenol suggests that the sensitivity of this analytical procedure increases with increase in the number of electronegative substituents in the molecule.

Back to tab navigation

Publication details

The article was received on 01 Jul 2002, accepted on 02 Sep 2002 and first published on 20 Sep 2002


Article type: Paper
DOI: 10.1039/B206350F
Citation: Analyst, 2002,127, 1463-1466
  •   Request permissions

    Determination of pentachlorophenol by negative ion chemical ionization with membrane introduction mass spectrometry

    T. A. Blake, X. Zheng, T. Aggerholm, F. R. Lauritsen and R. G. Cooks, Analyst, 2002, 127, 1463
    DOI: 10.1039/B206350F

Search articles by author

Spotlight

Advertisements