Issue 6, 2001

Zeolite-catalyzed cyclocondensation reaction for the selective synthesis of 3,4-dihydropyrimidin-2(1H)-ones

Abstract

A zeolite catalyzed, single step and environmentally friendly process for the synthesis of dihydropyrimidinones, a pharmacologically important class of compounds, is reported. Reusability of the catalyst and the ease of separation of pure product, selectively and in high yields in comparison to the classical Biginelli reaction, are a few of the unique features of this process.

Article information

Article type
Paper
Submitted
22 Aug 2001
First published
09 Nov 2001

Green Chem., 2001,3, 305-306

Zeolite-catalyzed cyclocondensation reaction for the selective synthesis of 3,4-dihydropyrimidin-2(1H)-ones

V. R. Rani, N. Srinivas, M. R. Kishan, S. J. Kulkarni and K. V. Raghavan, Green Chem., 2001, 3, 305 DOI: 10.1039/B107612B

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