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Issue 6, 2001
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Zeolite-catalyzed cyclocondensation reaction for the selective synthesis of 3,4-dihydropyrimidin-2(1H)-ones

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Abstract

A zeolite catalyzed, single step and environmentally friendly process for the synthesis of dihydropyrimidinones, a pharmacologically important class of compounds, is reported. Reusability of the catalyst and the ease of separation of pure product, selectively and in high yields in comparison to the classical Biginelli reaction, are a few of the unique features of this process.

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Publication details

The article was received on 22 Aug 2001 and first published on 09 Nov 2001


Article type: Paper
DOI: 10.1039/B107612B
Citation: Green Chem., 2001,3, 305-306
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    Zeolite-catalyzed cyclocondensation reaction for the selective synthesis of 3,4-dihydropyrimidin-2(1H)-ones

    V. R. Rani, N. Srinivas, M. R. Kishan, S. J. Kulkarni and K. V. Raghavan, Green Chem., 2001, 3, 305
    DOI: 10.1039/B107612B

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