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Issue 4, 2001
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Uncatalysed reactions in water: Part 2. Preparation of 3-carboxycoumarins

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Abstract

A simple, efficient and environmentally friendly procedure has been developed for the reaction of Meldrum’s acid with salicylaldehydes. 3-Carboxycoumarins 5 were synthesised in high yields (78–96%) and excellent selectivities (95–98%) by carrying out the reaction in water at reflux for 10 h, avoiding the addition of any catalyst.

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Publication details

The article was received on 26 Feb 2001 and first published on 27 Jun 2001


Article type: Paper
DOI: 10.1039/B101822C
Citation: Green Chem., 2001,3, 173-174
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    Uncatalysed reactions in water: Part 2. Preparation of 3-carboxycoumarins

    R. Maggi, F. Bigi, S. Carloni, A. Mazzacani and G. Sartori, Green Chem., 2001, 3, 173
    DOI: 10.1039/B101822C

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