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Department of Chemistry, University of Southampton, Highfield, Southampton, UK
E-mail: tb2@soton.ac.uk;
; Fax: +44 (0)23 80592991;
; Tel: +44 (0)23 80592974
b
Oswel Research Products Ltd., Medical and Biological Sciences Building, University of Southampton, Bassett Crescent East, Southampton, UK
E-mail: oswel@compuserve.com;
; Fax: +44 (0)23 80592982/3;
; Tel: +44 (0)23 80592984/5
Chem. Commun., 2001, 1480-1481
DOI:
10.1039/B104421B
Received
18 May 2001,
Accepted
26 Jun 2001
First published online
23 Jul 2001
Linear, single stranded probes incorporating a fluorophore and
an acridine moiety are weakly fluorescent until hybridised to a
complementary target nucleic acid whereupon fluorescence increases due to
reduced quenching.
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