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Issue 12, 2001
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Concise total syntheses of epothilone A and C based on alkyne metathesis

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Abstract

A ring closing alkyne metathesis reaction catalyzed by the molybdenum complex 26 followed by a Lindlar reduction of the resulting cycloalkyne product opens an efficient and stereoselective entry into epothilone A and C.

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Publication details

The article was received on 20 Feb 2001, accepted on 08 May 2001 and first published on 25 May 2001


Article type: Communication
DOI: 10.1039/B101669P
Citation: Chem. Commun., 2001,0, 1057-1059
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    Concise total syntheses of epothilone A and C based on alkyne metathesis

    A. Fürstner, C. Mathes and K. Grela, Chem. Commun., 2001, 0, 1057
    DOI: 10.1039/B101669P

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