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Issue 3, 2001
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Modified guanidines as chiral superbases: application to asymmetric Michael reaction of glycine imine with acrylate or its related compounds

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Abstract

Modified guanidines efficiently catalysed the asymmetric Michael reaction of a prochiral glycine derivative with acrylate or its related compounds either in solution or without a solvent under simple and mild conditions (>95% ee).

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Publication details

The article was received on 16 Nov 2000, accepted on 13 Dec 2000 and first published on 18 Jan 2001


Article type: Communication
DOI: 10.1039/B009193F
Citation: Chem. Commun., 2001,0, 245-246
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    Modified guanidines as chiral superbases: application to asymmetric Michael reaction of glycine imine with acrylate or its related compounds

    T. Ishikawa, Y. Araki, T. Kumamoto, H. Seki, K. Fukuda and T. Isobe, Chem. Commun., 2001, 0, 245
    DOI: 10.1039/B009193F

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