α-Bromoacrylamides (1) reacted with aldehydes or ketones, in the presence of SmI2 at −78 °C in THF, within 5 min to produce Baylis–Hillman type reaction products (2) through an anionic process using vinylsamarium Grignard species in good yields (52–89%).
A novel C–C bond formation by Baylis–Hillman type reaction mediated by SmI2: an effective approach to α-hydroxyalkylacrylamide synthesis
S. W. Youn, H. S. Park and Y. H. Kim, Chem. Commun., 2000, 2005 DOI: 10.1039/B006495P
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