Asymmetric chemo- and regiospecific addition of organozinc reagents to Baylis–Hillman derived allylic electrophiles
Abstract
The copper-catalysed SN2′ addition of
ZnR2 to allylic
(Z)-ArCHC(CH2X)(CO2Et) (X = Br, Cl,
OSO2Me) fashions only
ArCH(R)C(CH2)(CO2Et); use of a chiral