Issue 17, 2000
From the journal:

Chemical Communications

Characterisation of a sugar epimerase enzyme involved in the biosynthesis of a vancomycin-group

Peter N. Kirkpatrick,a   Wendy Scaife,a   Tina M. Hallis,b   Hung-wen Liu,b   Jonathan B. Spencera  and  Dudley H. Williams*a  

* Corresponding authors

a Cambridge Centre for Molecular Recognition, Department of Chemistry, Lensfield Road, Cambridge, UK
E-mail: dhw1@cam.ac.uk

b Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA

Abstract

An enzyme involved in the biosynthesis of the 4-epi-vancosamine substituents of a vancomycin group antibiotic has been expressed and its role as a TDP-4-keto-6-deoxyglucose-3,5-epimerase demonstrated.

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Article information

DOI
https://doi.org/10.1039/B004463F
Article type
Communication
Submitted
05 Jun 2000
Accepted
04 Jul 2000
First published
31 Jul 2000

Chem. Commun., 2000, 1565-1566

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Characterisation of a sugar epimerase enzyme involved in the biosynthesis of a vancomycin-group antibiotic

P. N. Kirkpatrick, W. Scaife, T. M. Hallis, H. Liu, J. B. Spencer and D. H. Williams, Chem. Commun., 2000, 1565 DOI: 10.1039/B004463F

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