Issue 1, 2000
From the journal:

Chemical Communications

The detection of intermediates in the ruthenium(ii) catalysed asymmetric hydrogenation of ketones using electrospray ionisation mass spectrometry

Jennifer A. Kenny,a   Kees Versluis,b   Albert J. R. Heck,b   Tim Walsgrovec  and  Martin Wills*a  

* Corresponding authors

a Department of Chemistry, University of Warwick, Coventry, UK
E-mail: m.wills@warwick.ac.uk.

b Department of Biomolecular Mass Spectrometry, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Sorbonnelaan 16, Utrecht, The Netherlands

c SmithKline Beecham Pharmaceuticals, Old Powder Mills, Nr Leigh, Tonbridge, Kent, UK

Abstract

The use of electrospray ionisation mass spectrometry for the detection of the intermediate species involved in the ruthenium(II)/amino alcohol reduction of ketones to alcohols is described.

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Article information

DOI
https://doi.org/10.1039/A908098H
Article type
Communication
Submitted
07 Oct 1999
Accepted
26 Nov 1999
First published
07 Jan 2000

Chem. Commun., 2000, 99-100

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The detection of intermediates in the ruthenium(II) catalysed asymmetric hydrogenation of ketones using electrospray ionisation mass spectrometry

J. A. Kenny, K. Versluis, A. J. R. Heck, T. Walsgrove and M. Wills, Chem. Commun., 2000, 99 DOI: 10.1039/A908098H

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