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Issue 24, 1999
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High yielding synthesis of dehydroamino acid and dehydropeptide derivatives

Abstract

By using a 4-dimethylaminopyridine (DMAP) catalysed reaction of β-hydroxyamino acid derivatives with tert- butyl pyrocarbonate [(Boc)2O], dehydroamino acid derivatives are obtained in high yields. The same methodology applied to dipeptides with a β-hydroxyamino acid residue gives the corresponding dipeptides with a dehydroamino acid residue.

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Article type: Paper
DOI: 10.1039/A904730A
Citation: J. Chem. Soc., Perkin Trans. 1, 1999, 3697-3703
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    High yielding synthesis of dehydroamino acid and dehydropeptide derivatives

    P. M. T. Ferreira, H. L. S. Maia, L. S. Monteiro and J. Sacramento, J. Chem. Soc., Perkin Trans. 1, 1999, 3697
    DOI: 10.1039/A904730A

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