A new synthon for the incorporation of [60]fullerene in macrocycles

Abstract

A bis(methano)fullerenedicarboxylic acid was obtained in four steps from C₆₀ as a new synthon for incorporation of the carbon sphere into macrocycles; the preparation of the target compound involves the tether-directed synthesis of a macrocyclic cis-2 bis(malonic acid diester) adduct of C₆₀, followed by selective ester deprotection, decarboxylation of the formed bis(malonic acid monoester) and removal of the tether.