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Issue 21, 1999
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Synthetic studies directed towards the potent cytotoxic natural product ottelione A: stereoselective construction of the complete framework

Abstract

A stereoselective strategy for the rapid acquisition of the complete framework (dideoxyottelione A) of the promising cytotoxic agent ottelione A, with four contiguous stereogenic centres on a hydrindane skeleton and a sensitive 4-methylenecyclohex-2-enone functionality, from the readily available Diels–Alder adduct of 1,2,3,4-tetrachloro-5,5-dimethoxycyclopentadiene and norbornadiene, is delineated.

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Article type: Paper
DOI: 10.1039/A907273J
Citation: Chem. Commun., 1999, 2193-2194
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    Synthetic studies directed towards the potent cytotoxic natural product ottelione A: stereoselective construction of the complete framework

    G. Mehta and D. Srinivasa Reddy, Chem. Commun., 1999, 2193
    DOI: 10.1039/A907273J

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