Issue 2, 1999

Synthesis and study of an acridine substituted Tröger’s base: preferential binding of the (–)-isomer to B-DNA

Abstract

The acridine substituted Tröger’s base 4 was prepared, resolved and the (–)-(7R,17R) enantiomer was shown to bind preferentially to calf-thymus B-DNA.

Article information

Article type
Paper

Chem. Commun., 1999, 161-162

Synthesis and study of an acridine substituted Tröger’s base: preferential binding of the (–)-isomer to B-DNA

A. Tatibouët, M. Demeunynck, C. Andraud, A. Collet and J. Lhomme, Chem. Commun., 1999, 161 DOI: 10.1039/A808822E

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