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Issue 15, 1998
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Use of polymer supported reagents for clean multi-step organic synthesis: preparation of amines and amine derivatives from alcohols for use in compound library generation

Abstract

The automated sequential application of polymer supported perruthenate (PSP) and polymer supported cyanoborohydride (PSCBH) in an oxidation–reductive amination procedure allowed the efficient transformation of simple alcohols into more complex amines which can be further derivatised by the use of polymer bound amino sulfonylpyridinium chlorides.

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Article type: Paper
DOI: 10.1039/A803611J
Citation: J. Chem. Soc., Perkin Trans. 1, 1998,0, 2239-2242
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    Use of polymer supported reagents for clean multi-step organic synthesis: preparation of amines and amine derivatives from alcohols for use in compound library generation

    S. V. Ley, M. H. Bolli, B. Hinzen, A. Gervois and B. J. Hall, J. Chem. Soc., Perkin Trans. 1, 1998, 0, 2239
    DOI: 10.1039/A803611J

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