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Issue 22, 1998
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Redox-active metal complexes for imaging hypoxic tissues: structure–activity relationships in copper(II) bis(thiosemicarbazone) complexes

Abstract

Reduction potential and lipophilicity of the copper(II) bis(thiosemicarbazone) complexes can be independently controlled by alkylation in the diketone backbone and the N-termini of the ligand, allowing optimisation of radiopharmaceuticals strongly selective for hypoxic tissues.

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Article type: Paper
DOI: 10.1039/A805957H
Citation: Chem. Commun., 1998,0, 2531-2532
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    Redox-active metal complexes for imaging hypoxic tissues: structure–activity relationships in copper(II) bis(thiosemicarbazone) complexes

    J. L. J. Dearling and P. J. Blower, Chem. Commun., 1998, 0, 2531
    DOI: 10.1039/A805957H

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