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Issue 10, 1998
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New procedures for the Juliá–Colonna asymmetric epoxidation: synthesis of (+)-clausenamide

Abstract

The oxidation of chalcone 1 to optically active epoxide 2 [a precursor of (+)-clausenamide (+)-3] may be effected using a 15-mer or 20-mer of L-leucine bound to a PEG based support; poly-L-leucines of this type may be used as immobilised catalysts in a fixed-bed reactor.

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Article type: Paper
DOI: 10.1039/A801450G
Citation: Chem. Commun., 1998,0, 1159-1160
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    New procedures for the Juliá–Colonna asymmetric epoxidation: synthesis of (+)-clausenamide

    M. W. Cappi, R. W. Flood, S. M. Roberts, J. Skidmore, N. M. Williamson, W. Chen, Y. Liao and J. A. Smith, Chem. Commun., 1998, 0, 1159
    DOI: 10.1039/A801450G

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