Stereocontrolled synthesis of (±)-α-pinguisene and (±)-pinguisenol
Abstract
Total synthesis of (±)-α-pinguisene 1 and (±)-pinguisenol 2, employing an orthoester Claisen rearrangement and an intramolecular diazo ketone cyclopropanation reaction for the stereospecific construction of vicinal quaternary carbon atoms, is described.