SCHEDULED MAINTENANCE
Synthesis of (2R)-2-bromodehydroquinic acid and
(2R)-2-fluorodehydroquinic
acid
Abstract
(2R)-2-Bromodehydroquinic acid and
(2R)-2-fluorodehydroquinic acid† have each been
synthesised in six steps from quinic acid via the common
intermediate 6. The syntheses exploit the selective protection of the
4-hydroxy group of the quinic acid lactone 3 with
tert-butyldimethylsilyl chloride.
† have each been
synthesised in six steps from quinic acid via the common
intermediate 6. The syntheses exploit the selective protection of the
4-hydroxy group of the quinic acid lactone 3 with
tert-butyldimethylsilyl chloride.
- This article is part of the themed collection: In memory of Chris Abell
Please wait while we load your content...
