Jump to main content
Jump to site search

Issue 5, 1997
Previous Article Next Article

Selection approaches to catalytic systems

Abstract

The key feature of enzymic catalysis is recognition of the transition state. Synthesis of designed systems rarely leads to successful catalysts as the rules for conformation and intermolecular interactions are to imperfectly understood. This review describes several current ‘selection’ approaches to the generation of systems that can recognise transitionstate analogues. Examples covered include catalytic antibodies, ribozymes, imprinted polymers. Combinatorial chemistry, and thermodynamic templating. All have the potential to yeild effective catalysts without prior design of every detail.

Back to tab navigation

Article type: Review Article
DOI: 10.1039/CS9972600327
Citation: Chem. Soc. Rev., 1997,26, 327-336
  •   Request permissions

    Selection approaches to catalytic systems

    P. A. Brady and J. K. M. Sanders, Chem. Soc. Rev., 1997, 26, 327
    DOI: 10.1039/CS9972600327

Search articles by author

Spotlight

Advertisements