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Issue 6, 1997
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Synthesis of the isomers of(1R)-3-(phenylthio)tropane-2-carboxylic acid methyl ester. A newclass of ligands for the dopamine transporter

Abstract

The syntheses of all four isomers of (1R)-3-(phenylthio)tropane-2-carboxylic acid methyl ester are described; the 2β,3β-isomer shows high affinity for the cocaine binding site on the dopamine transporter.

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Article type: Paper
DOI: 10.1039/A608238F
Citation: Chem. Commun., 1997,0, 555-556
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    Synthesis of the isomers of (1R)-3-(phenylthio)tropane-2-carboxylic acid methyl ester. A new class of ligands for the dopamine transporter

    M. Thiruvazhi, P. Abraham, M. J. Kuhar and F. Ivy Carroll, Chem. Commun., 1997, 0, 555
    DOI: 10.1039/A608238F

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