Jump to main content
Jump to site search

Issue 9, 1997
Previous Article Next Article

Molecular Imprint Based Radioassay for Direct Determination ofS-Propranolol in Human Plasma


Molecular imprints of S-propranolol have been applied to the development of a radiolabelled assay, which is conceptually identical to radioimmunoassay, for direct determination of the concentration of S-propranolol in biofluids. Determination of S-propranolol in human plasma and urine was used as a model system. The imprint based assay measured plasma and urine concentrations in the range of 20 to 1000 nM with accuracies of 89–107% and 91–125%, and precisions of 3–13% and 1–7%, respectively. The results demonstrate that it is possible to carry out molecular imprint based assays of biological samples without prior sample clean up.

Back to tab navigation

Article type: Paper
DOI: 10.1039/A703977H
Citation: Anal. Commun., 1997,34, 233-235
  •   Request permissions

    Molecular Imprint Based Radioassay for Direct Determination of S-Propranolol in Human Plasma

    H. Bengtsson, U. Roos and L. I. Andersson, Anal. Commun., 1997, 34, 233
    DOI: 10.1039/A703977H

Search articles by author