The use of a polymer, prepared in the presence of racemic propranolol
in order to form a ‘molecular imprint’, for the highly
selective extraction of the drug from a variety of aqueous media,
including biological samples, is described. It is shown that the
conditions chosen for elution of the adsorbed propranolol are extremely
important to ensure selectivity. Thus eluents based on
methanol–water 1% TEA proved to provide greater selectivity than
those based on methanol–water 1% TFA.
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