Issue 17, 1995

Stereochemical studies on the proposed spiro intermediate for the biosynthesis of the natural porphyrins: determination by a novel X-ray method of the absolute configuration of the spirolactam which inhibits cosynthetase

Abstract

A novel X-ray analysis, combined with correlations by circular dichroism, has been used to establish the (R)-configuration at the stereocentre in that enantiomer of the spirolactam 4 which strongly inhibits uroporphyrinogen III synthase.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1995, 1789-1790

Stereochemical studies on the proposed spiro intermediate for the biosynthesis of the natural porphyrins: determination by a novel X-ray method of the absolute configuration of the spirolactam which inhibits cosynthetase

A. C. Spivey, A. Capretta, C. S. Frampton, F. J. Leeper and A. R. Battersby, J. Chem. Soc., Chem. Commun., 1995, 1789 DOI: 10.1039/C39950001789

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements