Examination of newly synthesized elongated and truncated analogues of the ion-channel-forming peptide, trichosporin-B-VIa (20 residues), for ion-channel-forming activity in lipid bilayer membranes and catecholamine secretion-inducing activity from adrenal chromaffin cells revealed that the natural compound has the optimal molecular length for both activities.
Y. Nagaoka, A. Iida, T. Kambara, K. Asami, E. Tachikawa and T. Fujita, J. Chem. Soc., Chem. Commun., 1995, 2203 DOI: 10.1039/C39950002203
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