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Issue 10, 1995
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Optically active (S)-ketone- and (R)-aldehyde-cyanohydrins via an (R)-oxynitrifase-catalysed transcyanation. Chemoenzymatic syntheses of 2-cyanotetrahydrofuran and 2-cyanotetrahydropyran

Abstract

(R)-Oxynitrilase catalyses the enantioselective decyanation of racemic ketone cyanohydrins and the enantioselective addition of HCN to ω-bromoaldehydes in one step.

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Article type: Paper
DOI: 10.1039/C39950000989
Citation: J. Chem. Soc., Chem. Commun., 1995, 989-990
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    Optically active (S)-ketone- and (R)-aldehyde-cyanohydrins via an (R)-oxynitrifase-catalysed transcyanation. Chemoenzymatic syntheses of 2-cyanotetrahydrofuran and 2-cyanotetrahydropyran

    E. Menéndez, R. Brieva, F. Rebolledo and V. Gotor, J. Chem. Soc., Chem. Commun., 1995, 989
    DOI: 10.1039/C39950000989

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