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Issue 7, 1994
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Synthesis and properties of a potential extracellular fluorescent probe for potassium

Abstract

Development of a new, selective, high affinity, fluorescent probe CD222, 2, for potassium is described. Coincidentally two related probes, CDF18, 3, and CTF18, 4, were prepared and showed selectivity for the cations sodium and calcium, respectively, and possible reasons for these differences are discussed. The bicyclic probe CD222, 2, with observed KD values for K+ ranging from 1 to 10 mmol dm–3, has potential applications as an extracellular probe for potassium.

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Article type: Paper
DOI: 10.1039/P29940001615
Citation: J. Chem. Soc., Perkin Trans. 2, 1994,0, 1615-1623
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    Synthesis and properties of a potential extracellular fluorescent probe for potassium

    R. Crossley, Z. Goolamali and P. G. Sammes, J. Chem. Soc., Perkin Trans. 2, 1994, 0, 1615
    DOI: 10.1039/P29940001615

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