Cyclization and molecular rearrangement under micellar and microemulsion conditions

Abstract

Reaction procedures for Beckmann rearrangement and cyclization can be improved substantially if carried out under micellar/microemulsion conditions. This mode of operation allows the use of dilute acids as against the conventional highly acidic medium with ease of product recovery and yield. Experimental results for a case example of D-(–)-N-carbamoyl phenyl glycine to phenyl hydantoin are presented and analysed.