The stereochemical course of substitution of sulfur by oxygen nucleophiles in five-membered cyclic phosphorothioates
Abstract
The replacement of non-bridging sulfur in five-membered cyclic phosphorothioates by oxygen nucleophiles in the presence of bromine occurs with retention of configuration and has allowed the 31P NMR signals of the diastereoisomeric tert-butyldiphenyl silyl esters of 2′,3′-cyclic adenosine monophosphate to be assigned.