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Issue 6, 1993
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Proof that the biosynthesis of vitamin B12 involves a reduction step in an anaerobic as well as an aerobic organism

Abstract

Labelling experiments with 2H and 3H prove that as cobyrinic acid is biosynthesised by the anaerobic bacterium Propionibacterium shermanii, its H–19 is derived from HR(and not HS) at C-4 of a reduced nicotinamide cofactor, so demonstrating that the biosynthetic pathway involves a reduction step.

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Article type: Paper
DOI: 10.1039/C39930000515
Citation: J. Chem. Soc., Chem. Commun., 1993,0, 515-517
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    Proof that the biosynthesis of vitamin B12 involves a reduction step in an anaerobic as well as an aerobic organism

    K. Ichinose, M. Kodera, F. J. Leeper and A. R. Battersby, J. Chem. Soc., Chem. Commun., 1993, 0, 515
    DOI: 10.1039/C39930000515

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