2-Acyl thiazolium salts as selective agents for the O-acylation of aromatic hydroxylamines
Abstract
2-Acyl-3,4-dimethylthiazolium triflates, modelled upon the biologically important 2-acyl thiamine derivatives, react in neutral media specifically with the oxygen atom of N-aryl hydroxylami'nes to give rise to tetrahedral intermediates, which collapse to the O-acyl derivatives under mildly basic conditions.