SCHEDULED MAINTENANCE
The intermediacy of the spiro-pyrrolenine for biosynthesis of uro'gen III is supported by synthesis of both enantiomers of the spiro-lactam 6 followed by demonstration that cosynthetase, the enzyme which forms uro'gen III, is inhibited over twenty times more strongly by one enantiomer than by the other.
M. A. Cassidy, N. Crockett, F. J. Leeper and A. R. Battersby, J. Chem. Soc., Chem. Commun., 1991, 384 DOI: 10.1039/C39910000384
To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.
If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...