Enantioselective approach to isodaucane sesquiterpenes. Total synthesis of (+)-aphanamol-I and (+)-2-oxo-isodauc-5-en-12-al
Abstract
A general approach to isodaucane sesquiterpenes from (R)-(+)-limonene, resulting in the total synthesis of (+)-aphanamol-I (3) and (+)-2-oxo-isodauc-5-en-12-al (5), is described.