The transformation of tryptophan to aspartic acid in peptides
Abstract
The tryptophan side chain is transformed by in situ generated ruthenium(VIII), to that of aspartic acid, in good yields; a multi-step degradation sequence is suggested on the basis of the transformations of tetrahydrocarbazole to adipic acid, valine to isobutyric acid, and phenylalanine to phenylacetic acid.