Photochemistry in micelles as a model for the in vivo phototoxicity of chlorpromazine
Abstract
The photochemical reactivity of chlorpromazine has been studied in an oxygenated solution containing micelles. The photochemical dehalogenation reaction which had previously only been observed in oxygen-free solutions was found to predominate. The relevance of this photoreaction and the micelle as a model for the in vivo phototoxicity of chlorpromazine is discussed.