Issue 21, 1981

Synthesis of 3-deoxy-D-manno-octulosonic acid (KDO)

Abstract

2,3 : 5,6-Di-O-isopropylidene-D-mannose has been converted by five sequential reaction (Witting reaction, deacetonation, hydrogenation, lactonisation, and isopropylidenation) into 2, 3-dideoxy-5, 6: 7, 8-di-O-isopropylidene-D-octonolactone from which KDO could readily be obtained by hydrolysis.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1981, 1139-1140

Synthesis of 3-deoxy-D-manno-octulosonic acid (KDO)

P. M. Collins, W. G. Overend and T. Shing, J. Chem. Soc., Chem. Commun., 1981, 1139 DOI: 10.1039/C39810001139

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