Issue 21, 1980

Asymmetric reduction of αβ-unsaturated ketones with lithium aluminium hydride partially decomposed by (–)-N-methylephedrine and N-ethylaniline

Abstract

The title asymmetric reaction is found to convert open chain enones into the corresponding optically active allylic alcohols in high optical (78–98% enantiomeric excess) and chemical (92–100%) yields.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1980, 1026-1027

Asymmetric reduction of αβ-unsaturated ketones with lithium aluminium hydride partially decomposed by (–)-N-methylephedrine and N-ethylaniline

S. Terashima, N. Tanno and K. Koga, J. Chem. Soc., Chem. Commun., 1980, 1026 DOI: 10.1039/C39800001026

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