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Issue 4, 1978
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Asymmetric induction in the borohydride reduction of carbonyl compounds by means of chiral phase-transfer catalysts. Part 2

Abstract

Reaction of carbonyl compounds with sodium borohydride in a two-phase system, in the presence of chiral ammonium salts containing a secondary hydroxy-group affords the corresponding carbinols with 0–32% enantiomeric excess. The optical yields are higher when the hydroxy group is β to the ‘onium’ function and the catalyst is conformationally more rigid.

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Article type: Paper
DOI: 10.1039/P19780000371
Citation: J. Chem. Soc., Perkin Trans. 1, 1978,0, 371-373
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    Asymmetric induction in the borohydride reduction of carbonyl compounds by means of chiral phase-transfer catalysts. Part 2

    S. Colonna and R. Fornasier, J. Chem. Soc., Perkin Trans. 1, 1978, 0, 371
    DOI: 10.1039/P19780000371

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