Jump to main content
Jump to site search

Issue 0, 1972
Previous Article Next Article

1,3,4,5-Tetrahydrobenz[cd]indoles and related compounds. Part I. A new synthesis of 3,4-dihydrobenz[cd]indol-5(1H)-one (Uhle's ketone)

Abstract

New syntheses of 4-carboxyindole-3-propionic acid (9) starting from 3-amino-4-chlorobenzoic acid are described. A process involving thermal decarboxylation of 2,4-dicarboxyindole-3-propionic acid (8) in aqueous alkali is shown to be suitable for the large-scale preparation of the diacid (9) and thence Uhle's ketone (1).

Back to tab navigation
Please wait while Download options loads

Article type: Paper
DOI: 10.1039/P19720001121
Citation: J. Chem. Soc., Perkin Trans. 1, 1972, 1121-1123
  •   Request permissions

    1,3,4,5-Tetrahydrobenz[cd]indoles and related compounds. Part I. A new synthesis of 3,4-dihydrobenz[cd]indol-5(1H)-one (Uhle's ketone)

    R. E. Bowman, T. G. Goodburn and A. A. Reynolds, J. Chem. Soc., Perkin Trans. 1, 1972, 1121
    DOI: 10.1039/P19720001121

Search articles by author