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In this issue
Features
Biology’s Nobel molecule factory
Three scientists who revealed the structure and workings of the ribosome have shared the 2009 Nobel prize in chemistry. Phillip Broadwith unravels the story
A redesign for life
Work in the fashionable new field of synthetic biology is gathering pace. Hayley Birch looks into some of the latest developments in a rapidly evolving area
Molecules made to measure
HIV protease inhibitors have been one of the big successes of rational drug design. Clare Sansom looks at the impact of structural biology on drug discovery
Design for life
A new drug for treating prostate cancer, developed by rational design and currently making its way through clinical trials, could improve the prognosis, says John Mann
40 years of crystal growth
The development of the British Association of Crystal Growth maps changes in the industry over the past 40 years. Hayley Birch caught up with members at this year’s conference
Opinions
Editorial: Ringing in the Nobels
Gunnar von Heijne of the Royal Swedish Academy of Sciences didn’t mince his words when he announced the 2009 winners of the Nobel prize in chemistry
Column: In the pipeline
Derek Lowe advises opening your mind during the screening cascade taken by potential drug targets, and remaining goal orientated at all times
Column: The crucible
Could red light and green tea really give ‘facial rejuvenation’? Philip Ball looks at the intriguing science behind this new claim
Column: Totally Synthetic
Iriomoteolide
Column: Undercover academic
Lab life
Poetic science
A year spent in a chemistry department led poet Diana Hendry to hunt out links between science and poetry. Are poets more open to science than scientists to poetry, she asks
Past Issues of Chemistry World
Useful Links
China News
Enamel regeneration makes scientists smile
25 August 2009
Chinese researchers are a step closer to being able to regrow tooth enamel in the mouth.
Heavy metal poisoning sparks protests in China
25 August 2009
Industrial pollution causes lead and cadmium poisoning in China, prompting protests and calls for improved regulation
China’s emissions to peak early
21 August 2009
New report suggests carbon emissions from China could peak in 2030, decades earlier than previously estimated
China drug scheme funds out of reach
19 August 2009
Funding through China’s multi-billion yuan drug development scheme could become harder to come by says programme representative
Gold nanoparticles detect cancer
19 August 2009
Ultrasensitive detection platform uses nanoparticles to measure levels of cancer biomarkers
Superhydrophobicity saves scalding
14 July 2009
Clothes could repel hot water with a Teflon-carbon nanotube composite coating
更多中文新闻
World News
The Commercial Chemist
06 November 2009
Chemistry World gets down to business with our weekly round-up of money and molecules
Loss of senior chemist throws further doubt on future of UK drugs council
06 November 2009
Former ACMD senior chemist Les King would join new independent drugs committee set up by dismissed scientist David Nutt
Monitoring asthma with mobile phones
06 November 2009
A mobile phone-based sensor can be used in measure nitric oxide in breath, a indicator for airway inflammation
Boron-based compounds inhibit key HIV enzyme
06 November 2009
Structures based on caged polyhedral clusters may lead to new way to treat drug resistant HIV
Enzyme binds both sides of the mirror
06 November 2009
Bacterial enzyme found to bind both enantiomers of a chiral molecule simultaneously
Silver coating gets gold star
06 November 2009
Scientists from the UK are waging war on hospital ‘superbugs’ with a highly effective antimicrobial organo-silver coating
Playing with ‘Russian-doll’ fullerenes
05 November 2009
Chinese chemists make ‘Russian-doll’-style fullerenes, containing three distinct molecules trapped within one another
Interview: Sweet Science
05 November 2009
David Jakeman talks about carbohydrates, drugs and meeting Darwin. Interview by Nicola Wise
Bolivia plans to lead the electric revolution
04 November 2009
Bolivia is to go it alone and start mining its lithium reserves – a move that will aid electric car production
New treatment hope for lupus patients
04 November 2009
Positive results from two late stage trials offer hope for sufferers of the autoimmune disease lupus
Single-base DNA resolution
04 November 2009
A fluorescent probe sensitive to differences at the single-base-level of DNA has been created by researchers in Japan
Cash lures top achievers away from US science
03 November 2009
Science is losing more of the cream of the academic crop to high-paying careers in other sectors
First tests for pesticide endocrine effects in US
03 November 2009
EPA orders chemical manufacturers to screen seven compounds to determine if they are endocrine disruptors
Omega comes first for brain imaging
02 November 2009
Remote-controlled miniature valves designed by US scientists can deliver tracers into the brain.
New way to find drugs' unintended targets
02 November 2009
New computational and statistical strategy identifies potential side effects and new targets for pharmaceutical drugs
Efficient Eucalyptus chemistry
02 November 2009
Eucalyptus leaves can be used as a greener way to produce a valuable chemical used in fragrances and pharmaceuticals
Acid solution for nanotube fibres
01 November 2009
Carbon nanotubes can be dissolved in chlorosulfonic acid for easy processing
How light gave life a helping hand
01 November 2009
A theory for how single-handed organic molecules came to be the building blocks of life
GM traces cause chemical feedstock shortage
30 October 2009
Chemical producers brace for shortages as thousands of tonnes of raw material are stranded in port due to traces of GM crops
Celebrating chemistry
30 October 2009
Today 800 chemists will gather to celebrate the 400th anniversary of the birth of chemistry as an academic subject
Acidity regulation in microfluidic channels
30 October 2009
Controlling pH in microfluidics could allow the activity of single enzymes to be measured, say Dutch scientists.
Two metals are better than one
29 October 2009
Zinc and alkali metals team up to metallate THF without breaking open the ring
Changes in atomic-scale structures observed in real time
29 October 2009
New ultrafast electron diffraction can focus on a nanometre-sized area and track structural changes at the femtosecond timescale
