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Chemical Communications

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Communication

Chem. Commun., 2009, 6795 - 6797, DOI: 10.1039/b915132j


Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray

Jing Zhang, Gwladys Pourceau, Albert Meyer, Sébastien Vidal, Jean-Pierre Praly, Eliane Souteyrand, Jean-Jacques Vasseur, François Morvan and Yann Chevolot


Two glycoconjugates bearing different DNA tags are mixed in solution with lectins; both interact with their specific lectin and the resulting complexes are sorted, according to their DNA sequences, at the surface of micro-reactors bearing the immobilised complementary DNA sequences.

Graphical abstract image for this article  (ID: b915132j)