RSC Publishing


Publishing

 

Cover image for Chemical Communications, select for current issue

Chemical Communications

Urgent high quality communications from across the chemical sciences.



Free access



Communication

Chem. Commun., 2009, 6985 - 6987, DOI: 10.1039/b912231a

Solid-phase synthesis of protected -amino phosphonic acid oligomers

Yoshitaka Ishibashi and Masato Kitamura

By establishing both a highly efficient phosphonamidate formation and a RuCp-catalyzed cleavage of an allyl linker, the solid-phase synthesis of Fmoc-(GlyP(OBn))6-OH/DIEA, a protected form of a new type of unnatural peptide -amino phosphonic acid oligomer (APO), has been realized.

Graphical abstract image for this article (ID: b912231a)