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Chem. Commun., 2009, 5135 - 5137, DOI: 10.1039/b911765b


Total synthesis of (+)-virgatusin via AlCl3-catalyzed [3+2] cycloaddition

Shanina D. Sanders, Andrea Ruiz-Olalla and Jeffrey S. Johnson


The AlCl3-catalyzed cycloaddition of a donor–acceptor (don–acc) cyclopropane and piperonal succinctly provides the core of virgatusin in a selective, high-yielding manner.

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