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Communication

Chem. Commun., 2009, 2881 - 2883, DOI: 10.1039/b902195g


New method to prepare very stable and biocompatible fluorescent silica nanoparticles

Shin-Woo Ha, Corinne E. Camalier, George R. Beck Jr.,Jin-Kyu Lee


A new synthetic method has been developed to prepare fluorescent silica nanoparticles without employing isothiocyanated dye molecules and (3-aminopropyl)triethoxysilane (APS) for the thiourea linkage formation; the resulting fluorescent silica nanoparticles show excellent photochemical, thermal and pH stabilities and a good biocompatibility with over 85% viability from various cell types.

Graphical abstract image for this article  (ID: b902195g)