Issue 42, 2015
From the journal:

Chemical Communications

Photoreactivity of the linker region of two consecutive G-quadruplexes formed by human telomeric DNA†

Yue Lia  and  Hiroshi Sugiyama*ab  

* Corresponding authors

a Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan
E-mail: hs@kuchem.kyoto-u.ac.jp

b Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Yoshida-ushinomiyacho, Sakyo-ku, Kyoto 606-8501, Japan

Abstract

We report the application of a photoreaction method for probing two consecutive G-quadruplexes formed by human telomeric DNA. This method can discriminate the loop structure located between two consecutive G-quadruplexes formed by eight TTAGGG repeats in K+ and Na+ solutions.

Graphical abstract: Photoreactivity of the linker region of two consecutive G-quadruplexes formed by human telomeric DNA

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Article information

DOI
https://doi.org/10.1039/C5CC01812A
Article type
Communication
Submitted
05 Mar 2015
Accepted
16 Apr 2015
First published
17 Apr 2015
This article is Open Access
Creative Commons BY license

Chem. Commun., 2015,51, 8861-8864

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Photoreactivity of the linker region of two consecutive G-quadruplexes formed by human telomeric DNA

Y. Li and H. Sugiyama, Chem. Commun., 2015, 51, 8861 DOI: 10.1039/C5CC01812A

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