Issue 11, 2000

Toluene dioxygenase-mediated oxidation of aromatic substrates with remote chiral centers

Abstract

Several aromatic substrates containing remote chiral centers were subjected to toluene and naphthalene dioxygenase expressed in blocked mutants and recombinant organisms yielding cis-diol metabolites with little or no kinetic resolution.

Article information

Article type
Communication
Submitted
16 Mar 2000
Accepted
17 Apr 2000
First published
08 May 2000

J. Chem. Soc., Perkin Trans. 1, 2000, 1669-1672

Toluene dioxygenase-mediated oxidation of aromatic substrates with remote chiral centers

V. Bui, T. V. Hansen, Y. Stenstrøm, D. W. Ribbons and T. Hudlicky, J. Chem. Soc., Perkin Trans. 1, 2000, 1669 DOI: 10.1039/B002143L

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